Youre comparing 12:16:47 in the morning, or 45 minutes till 1am against 9pm in the same day. Chronologically this makes perfect sense. If you were to change "now" to the day after, referencing 12:16am of the following day, it returns true.
var start = new Date('2021-01-29T21:00:00.000Z');
var now = new Date('2021-01-29T00:16:47.797Z');
console.log(now >= start); //false
var start = new Date('2021-01-29T21:00:00.000Z');
var now = new Date('2021-01-30T00:16:47.797Z');
console.log(now >= start); //true
与恶龙缠斗过久,自身亦成为恶龙;凝视深渊过久,深渊将回以凝视…