STA (single-threaded apartment) and MTA (multi-threaded apartment) are to do with COM. COM components can be designed to be accessed by a single thread, in which case it they are hosted in an STA, or they can be made internally thread safe, and hosted in an MTA. A process can have only one MTA, but many STAs. If you're only going to consume COM components all that you really need to know is that you have to match the apartment to the component or nasty things will happen.
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