I'd just read the first row and see which gives you more columns:
import pandas as pd
tab = pd.read_csv(data_file, nrows=1, sep='').shape[1]
com = pd.read_csv(data_file, nrows=1, sep=',').shape[1]
if tab > com:
df = pd.read_csv(data_file, sep='')
else:
df = pd.read_csv(data_file, sep=',')
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