Kip's solution should work on Opera and Safari if you change the CSS to:
<style>
#wrap { width: 600px; height: 390px; padding: 0; overflow: hidden; }
#frame { width: 800px; height: 520px; border: 1px solid black; }
#frame {
-ms-zoom: 0.75;
-moz-transform: scale(0.75);
-moz-transform-origin: 0 0;
-o-transform: scale(0.75);
-o-transform-origin: 0 0;
-webkit-transform: scale(0.75);
-webkit-transform-origin: 0 0;
}
</style>
You might also want to specify overflow: hidden on #frame to prevent scrollbars.
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