Several possibilities, here's my favorite
library(data.table)
setDT(df)[, if(+var(number)) .SD, by = from]
# from number
# 1: 2 1
# 2: 2 2
Basically, per each group we are checking if there is any variance, if TRUE
, then return the group values
With base R, I would go with
df[as.logical(with(df, ave(number, from, FUN = var))), ]
# from number
# 3 2 1
# 4 2 2
Edit: for a non numerical data you could try the new uniqueN
function for the devel version of data.table
(or use length(unique(number)) > 1
instead
setDT(df)[, if(uniqueN(number) > 1) .SD, by = from]
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