Umbrella frameworks only make sense if you are the only distributor of all the involved frameworks, and you will be packaging all the frameworks together as a single versioned package which will be upgraded together. If that is your situation, then that's fine, but this is a very unusual situation. In the Cocoa development world, it is exceedingly unusual for anyone but Apple to be in this situation.
To the first point, umbrella frameworks only make sense if you are the only distributor of the given frameworks. For example, say that you wanted to include libcurl as part of your umbrella framework. Now some other packager also wants to include libcurl as part of his umbrella framework. Now we have a link-time collision that can lead to either link errors or worse, undefined runtime behavior. I've chased these down myself. They're extremely unpleasant. The only way to avoid this is for there to be only a single version of each framework/library. Umbrella frameworks encourage the opposite.
Even if you are just breaking up your own code into subpieces, this means that other vendors might use your sub-frameworks in their own umbrella frameworks, leading back to the same problem. Remember, if you say it's ok for you as a third party to use umbrella frameworks, then it's ok for other vendors too.
To the second point, umbrella frameworks only make sense if you control the versioning of all the sub-frameworks. Trying to patch one piece of an inter-dependent set of frameworks is almost always a disaster in my experience.
The OS vendor has an unusual situation due to the size and ubiquity of their system. Things that make sense at one scale often do not make sense at another. NSResponder is completely correct about that. The trade-offs are different when you're providing a complete, multi-thousand package environment that is the basis of every program written for the platform. But even Apple has only a handful of large umbrella frameworks, and they are always wrappers around libraries that they provide and control the version of. This is mostly to simplify the work of developers who would otherwise have to chase down dozens of libraries and frameworks to get something to compile. No third party has that situation, and so it is very rare that a third-party needs this solution. Asking your customer to link two libraries is completely different then asking them to link 20. If you're providing 20 frameworks that all work together and you control, then maybe you should use an umbrella, but also maybe you have too many frameworks for a third party.
Most of my discussion here is in terms of OS X. On iOS it is a non-issue for third-parties. Static libraries must never link other static libraries due to the collisions that will certainly occur.
In theory, most of the issues I've discussed here a fundamentally technical limitations of the linker. The linker doesn't have a good way to manage multiple versions of libraries and so collisions are a serious problem. .NET assemblies try to provide more flexibility around this. I'm not familiar enough with .NET development to say whether this has been successful or not. My experience with large multi-component systems is that simpler, less flexible solutions are best for most problems. (But then, the grass is always greener....)
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