I apologize that the question was vague. However we had no clue what was causing the problem so what facts would have been relevant?
At any rate it turns out we have two web apps running under IIS, both are trying to create ActiveX components. As soon as we turn one of the web apps off the problem goes away.
After we verified this behavior, we tried calling some simple ActiveX components (like excel). Lo and behold exactly the same behavior as long as there are more than two web apps running.
Our solution for now is to host the second web app elsewhere.
与恶龙缠斗过久,自身亦成为恶龙;凝视深渊过久,深渊将回以凝视…