This makes a list with five references to the same list:
data = [[None]*5]*5
Use something like this instead which creates five separate lists:
>>> data = [[None]*5 for _ in range(5)]
Now it does what you expect:
>>> data[0][0] = 'Cell A1'
>>> print data
[['Cell A1', None, None, None, None],
[None, None, None, None, None],
[None, None, None, None, None],
[None, None, None, None, None],
[None, None, None, None, None]]
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