SELECT * FROM `some_table`
WHERE
CONCAT_WS('|',`column1`,`column2`,`column3`,`column4`,`column64`) # single condition, many columns
LIKE '%VT%'
Voila.
The '|' separator, by the way, is to prevent you finding coincidental matches where, e.g., column1 ends in 'V' and column2 starts with 'T', which would give you a false positive in a search for "VT".
I'm not sure if the above method is faster than the OR
method (I would guess they're the same speed) , but it definitely involves less typing if you're writing the query by hand.
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