A little update on @alecxe response for Python 3 (io.BytesIO instead of StringIO.StringIO) and Django >= 1.5 (content_type instead of mimetype), with the fully in-memory file assembly that has since been implemented by @jmcnamara ({'in_memory': True}) !
Here is the full example :
import io
from django.http.response import HttpResponse
from xlsxwriter.workbook import Workbook
def your_view(request):
output = io.BytesIO()
workbook = Workbook(output, {'in_memory': True})
worksheet = workbook.add_worksheet()
worksheet.write(0, 0, 'Hello, world!')
workbook.close()
output.seek(0)
response = HttpResponse(output.read(), content_type="application/vnd.openxmlformats-officedocument.spreadsheetml.sheet")
response['Content-Disposition'] = "attachment; filename=test.xlsx"
output.close()
return response
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