You need to disable verification of the APK during ADB install. If the setting in Security is greyed out or isn't working as it should try shelling into the device and, depending on which settings database the setting is in per your API level (Global, System, Secure) run
$ adb shell settings put global verifier_verify_adb_installs 0
If you can actually set it, it will prevent checking of APKs over ADB.
Sometimes you will need to disable the package verifier as well using:
$ adb shell settings put global package_verifier_enable 0
On KitKat, you can see here that these settings are in the Global database:
http://androidxref.com/4.4.2_r2/xref/frameworks/base/core/java/android/provider/Settings.java#5015
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