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r - How do I change a single value in a data.frame?

Could anyone explain how to change a single cell in a data.frame to something else. Basically I just want to rename that one cell, not all cells which matches it. I can′t use the edit() command because it will screw up my script since im using the data.frame on several occasions.

Thanks in advance

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data.frame[row_number, column_number] = new_value

For example, if x is your data.frame:

x[1, 4] = 5

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