Set up a named vector, describing the link between colour and integers (i.e. specifically how the strings map to the integers):
colors=c(1,2,3)
names(colors)=c("Red", "Blue", "Orange")
Now use the named vector to generate a list of numbers associated with the colours in your data frame:
>colors[c("Red","Blue","Blue","Orange")]
Red Blue Blue Orange
1 2 2 3
UPDATE to address questions below. Here's an example of what I think you're trying to do.
dataframe=data.frame(Gender=c("F","F","M","F","F","M"))
strings=sort(unique(dataframe$Gender))
colors=1:length(strings)
names(colors)=strings
dataframe$Colours=colors[dataframe$Gender]
Can have a look at the result:
> dataframe
Gender Colours
1 F 1
2 F 1
3 M 2
4 F 1
5 F 1
6 M 2
Note that this example assumes that you have no specific mapping between Gender and Colours in mind. If this is really the case, then it might be simpler to just follow the comment from @alexis_laz instead.
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