If it is a USB reader, you should find the .net drivers that come with it, such that you get a class which provides the IO and perhaps more functionality.
If the scanner has internally a USB to Serial converter, then you should see in your Device Manager which COM port is in use by the scanner. In that case, you can use the SerialPort
class for communication to the device. Note that you should set the settings (i.e. baudrate, parity bit, stop bit, etc) correct before you can have any communication.
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